Process Transformation for Better IT Service Delivery in the Pharmaceutical Industry

Soaring drug development costs, patent expiration and reduction in the number of blockbuster drugs are driving pharma companies to look at IT-enabled productivity. The traditional approach of 'working for business' is evolving into a 'working with business' model. Pharma... IT processes must support this transformation and also manage mandatory regulatory requirements including the Food and Drug Administration's (FDA) Code of Federal Regulations (CFR) 21 Part 11 and Computer System Validation (CSV). In addition, IT process transformation must be able to deliver the right products and meet the needs of internal and external stakeholders.

Streamlining Drug Discovery Research by Leveraging Grid Workflow Manager

Pharmaceutical companies are under pressure to speed up time-to-market and reduce costs for producing novel drug molecules. One of the key enablers to enhance productivity is grid computing. Grid allows linking up as many... processors, storage and/or memory of distributed computers to make more efficient use of available computing resources. The benefits of grid computing include cost savings, faster time-to-market, enhanced collaboration and optimal use of existing computing resources. Infosys has developed Discovery Research Workflow on Grid (DRWG), a workflow solution to automate and accelerate gene discovery research. DRWG enables the user to customize a pipeline of compute intensive tasks, which can be executed on heterogeneous platforms. This paper discusses how high throughput functional annotation of genomic DNA sequences or profiling groups of protein sequences can leverage grid computing services.

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